MECHANICAL STABILITY OF SERUM CHOLINESTERASE
نویسندگان
چکیده
منابع مشابه
The Clinical Stability of Serum Cholinesterase Activity.
Intra-individual variation of serum cholinesterase activity as determined in 82 normal adults studied 373 times over periods up to 5 years is found to be relatively low. The over-all coefficient of variation was 8.4, the linear correlation between the first and subsequent tests in the same person was r = .87 (first versus second test in 82 subjects) and r = .90 (first versus seventh test in 14 ...
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Objective: To determine whether serum cholinesterase level has a prognostic value in human acute organophosphorus poisoning. Design: Cohort (prospective) prognosis study. Setting: Medical ICU at University Hospital. Patients: Thirty consecutive patients admitted to the ICU for acute organophosphate poisoning. Measurements: Serum cholinesterase level was measured in all patients at the time of h...
متن کاملStructure of human serum cholinesterase.
Human cholinesterase has recently been sequenced and cloned. It is a glycoprotein of 4 identical subunits, each subunit containing 9 carbohydrate chains and 3.5 disuljide bonds. Protein folding is likely to be very similar in human cholinesterase and Torpedo acetylcholinesterase. The cholinesterases have no significant sequence homology with the serine proteases and seem to belong to a separate...
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S EVERAL SUGGESTIONS have been made to explain the parallelism between serum cholinesterase and serum albuniin levels in chronic liver disease-first recognized by Faber (i), and since, by many othersand the moderate fall in serum cholinesterase found to occur ill normal persons after the infusion of albumin (2). Kunkel and Ward (3) suggested that a normal serum albumin level was needed for the ...
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The dibucaine number (DN) was determined for serum cholinesterase (EC 3.1.1.8, SChE) in plasma samples. The ones with a DN of 79-82 were used, because they had the "usual" SChE variant. The enzyme was assayed colorimetrically by the reaction of 5,5'-dithiobis-[2-nitrobenzoic acid] (DTNB) with the free sulfhydryl groups of thiocholine that were produced by the enzyme reaction with butrylthiochol...
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ژورنال
عنوان ژورنال: British Journal of Anaesthesia
سال: 1974
ISSN: 0007-0912
DOI: 10.1093/bja/46.11.837